BETA-GLUCAN FOR USE IN MODULATION OF AN IMMUNE RESPONSE IN A REMISSION

摘要

The invention discloses a use of beta-glucan in order to increase anti-tumor immunity in remission after the treatment of solid tumors, where after the long-term peroral usage the concentration of the CD8+ lymphocytes, CD19+ lymphocytes increases and the level of lgG3, IgA, CD16+56+ increases. The clinical study has shown the efficiency of the preventive treatment during the immunosensitive cancer such as breast cancer. In the preferable arrangement beta-glucan is fungal β (1,3/1,6) glucan prepared from the oyster mushroom. During the sequential usage in the first phase a high dose of beta-glucan is used and in the second phase a low dose of beta-glucan is used, whereby the high dose of beta-glucan is at least twice the low dose of beta- glucan. The administration is long-term and continuous without sequences where the dosage is completely omitted. The high dose of beta-glucan can daily range from 600 mg to 800 mg, preferably 700 mg and low dose of beta-glucan can daily range from 50 mg to 300 mg, preferably 100 mg or 200 mg.