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Canine adenovirus vector

机译:犬腺病毒矢量

摘要

The present invention relates to the field of CAdV vector vaccines, and in particular to promoters suitable for the expression of target antigens derived from such vector vaccines. Disclosed and claimed are recombinant canine adenoviruses, methods of making them, their use (in immunological, immunogenic vaccines or therapeutic compositions, or of DNA cloning, replication or expression) As a vector for and as a method of using the composition and vector), expression products derived therefrom, and use of the expression products. Further disclosed and claimed are a truncated EHV4 promoter, an expression cassette containing the promoter, and a recombinant virus and plasmid containing the promoter or expression cassette.
机译:本发明涉及CADV载体疫苗的领域,特别涉及适于表达衍生自这种载体疫苗的靶抗原的启动子。公开和要求保护的是重组犬腺病毒,制备它们的方法,它们的用途(在免疫学,免疫原性疫苗或治疗组合物中,或DNA克隆,复制或表达)作为载体,以及使用组合物和载体的方法),表达产品由此衍生,并使用表达产品。进一步公开和要求保护是截短的EHV4启动子,含有促进剂的表达盒,以及含有促进剂或表达盒的重组病毒和质粒。

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