首页> 外国专利> Composition for use in treating or preventing viral or bacterial infections in a subject undergoing anti-tumor chemotherapy, leukemia treatment or aids therapy comprising L. reuteri LER03 and/or L. salivarius LS06

Composition for use in treating or preventing viral or bacterial infections in a subject undergoing anti-tumor chemotherapy, leukemia treatment or aids therapy comprising L. reuteri LER03 and/or L. salivarius LS06

机译:用于治疗或预防抗肿瘤化疗,白血病治疗或艾滋病治疗的受试者中病毒或细菌感染的组合物。 Reuteri ler03和/或 l。唾液 ls06

摘要

A composition for use as adjunctive therapy to antitumor chemotherapeutic treatments, acquired immunodeficiency syndrome treatments and leukemia treatments is described. The composition includes a strain of bacteria Lactobacillus reuteri LRE 03 DSM 23879 which is able to strongly stimulate the production of pro-inflammatory cytokines (Th1) interferon INF-gamma, the cytokines exhibiting a marked antiviral and/or antibacterial activity, and/or a bacterial strain Lactobacillus salivarius LS06 DSM 26037 which is able to strongly stimulate dendritic cell production, the dendritic cells exhibiting a marked antiviral and/or antibacterial activity. The composition can include one or more of: a bacterial strain able to produce, when ingested, bacterial exopolysaccharides EPS; and/or a plant polysaccharide such as tara gum; and/or an Aloe arborescens gel; and/or a gelling agent such as sodium alginate and/or a highly bioavailable zinc internalized into a tyndallized bacterial cell.
机译:描述了用作抗肿瘤化学治疗治疗的辅助治疗的组合物,所获得的免疫缺陷综合征治疗和白血病治疗。该组合物包括细菌菌株乳酸杆菌菌膜 LRE 03 DSM 23879,其能够强烈地刺激促炎细胞因子(TH1)干扰素INF-γ的产生,表现出明显的抗病毒和/或抗菌活性,和/或细菌菌株乳酸杆菌唾液柱 LS06 DSM 26037能够强烈刺激树突细胞产生,树突细胞表现出明显的抗病毒和/或抗菌活性。该组合物可包括一种或多种:在摄入的细菌外碳EPS时能够产生的细菌菌株;和/或植物多糖如塔拉胶;和/或芦荟植物植物凝胶;和/或胶凝剂如藻酸钠和/或高度生物可利用的锌,内化为钨的细菌细胞。

著录项

  • 公开/公告号US11077153B2

    专利类型

  • 公开/公告日2021-08-03

    原文格式PDF

  • 申请/专利权人 CHIARA BENASSAI;ELENA MOGNA;VERA MOGNA;

    申请/专利号US201515307757

  • 发明设计人 GIOVANNI MOGNA;

    申请日2015-04-30

  • 分类号A61K35/744;A61K35/74;A61K9/06;A61K35/745;A61K35/747;

  • 国家 US

  • 入库时间 2022-08-24 20:18:51

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