首页> 外国专利> A COMPOSITION FOR USE IN TREATING OR PREVENTING VIRAL OR BACTERIAL INFECTIONS IN A SUBJECT UNDERGOING ANTI-TUMOR CHEMOTHERAPY, LEUKEMIA TREATMENT OR AIDS THERAPY COMPRISING L. REUTERI LER03 AND/OR L. SALIVARIUS LS06.

A COMPOSITION FOR USE IN TREATING OR PREVENTING VIRAL OR BACTERIAL INFECTIONS IN A SUBJECT UNDERGOING ANTI-TUMOR CHEMOTHERAPY, LEUKEMIA TREATMENT OR AIDS THERAPY COMPRISING L. REUTERI LER03 AND/OR L. SALIVARIUS LS06.

机译:用于治疗或预防正在接受抗肿瘤化学疗法,白血病治疗或艾滋病治疗的受试者的病毒性或细菌性感染的组合物,该组合物包括罗伊氏乳杆菌LER03和/或L. SALIVARIUS LS06。

摘要

A composition for use as adjunctive therapy to antitumor chemotherapeutic treatments, acquired immunodeficiency syndrome treatments and leukemia treatments is described. The composition includes a strain of bacteria Lactobacillus reuteri LRE 03 DSM 23879 which is able to strongly stimulate the production of pro-inflammatory cytokines (Th1) interferon INF-gamma, the cytokines exhibiting a marked antiviral and/or antibacterial activity, and/or a bacterial strain Lactobacillus salivarius LS06 DSM 26037 which is able to strongly stimulate dendritic cell production, the dendritic cells exhibiting a marked antiviral and/or antibacterial activity. The composition can include one or more of: a bacterial strain able to produce, when ingested, bacterial exopolysaccharides EPS; and/or a plant polysaccharide such as tara gum; and/or an Aloe arborescens gel; and/or a gelling agent such as sodium alginate and/or a highly bioavailable zinc internalized into a tyndallized bacterial cell.
机译:描述了用作抗肿瘤化学疗法,获得性免疫缺陷综合症疗法和白血病疗法的辅助疗法的组合物。该组合物包括能强烈刺激促炎性细胞因子(Th1)干扰素INF-γ产生的罗伊氏乳杆菌LRE 03 DSM 23879菌株,所述细胞因子表现出显着的抗病毒和/或抗菌活性,和/或细菌菌株唾液乳杆菌LS06 DSM 26037,其能够强烈刺激树突状细胞的产生,该树突状细胞表现出显着的抗病毒和/或抗菌活性。该组合物可以包括一种或多种:当被摄入时能够产生细菌胞外多糖EPS的细菌菌株;和和/或植物多糖如塔拉胶;和/或芦荟树胶;和/或胶凝剂(例如海藻酸钠)和/或内化到扁桃体化细菌细胞中的高生物利用度锌。

著录项

  • 公开/公告号EP3145518A1

    专利类型

  • 公开/公告日2017-03-29

    原文格式PDF

  • 申请/专利权人 MOGNA GIOVANNI;

    申请/专利号EP20150726675

  • 发明设计人 MOGNA GIOVANNI;

    申请日2015-04-30

  • 分类号A61K35/74;A61P31/12;A61P31/04;

  • 国家 EP

  • 入库时间 2022-08-21 14:03:08

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