THE USE OF GROWTH FACTOR-ENCODING NUCLEOSIDE-MODIFIED MRNA FOR PERIODONTAL TISSUE AND BONE REGENERATION

摘要

The present disclosure relates to compositions and methods for inducing regeneration of periodontal tissue and bone in a subject. In certain aspects, the composition comprises at least one isolated RNA encoding at least one growth factor, or fragment or variant thereof. In one aspect, the composition comprises a nucleoside-modified RNA encoding at least one growth factor, or fragment or variant thereof.