Disclosed herein are therapeutic compositions comprising omega-3 fatty acid mixtures and ubiquinone, and a method improving heart health comprising administering an effective amount of a therapeutic composition comprising omega-3 fatty acid mixtures and ubiquinone. According to embodiments, therapeutic compositions for improved heart health are provided comprising: vitamin B6; folate; vitamin B12; chromium; an omega-3 fatty acid component, comprising: docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA), and L-carnitine fumarate; and ubiquinone. The therapeutic compositions are effective in supporting heart health and healthy aging.
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