BIOMIMETIC BIOMATERIAL AND PRODUCTION METHOD THEREOF

摘要

This invention relates to production method comprising processes of slip casting and freeze drying, which is a hybrid system, for developing hydroxyapatite-containing bio-ceramic developed by combined utilization of medical and engineering sciences in order to use on bone diseases, wherein it discloses a new hybrid system comprising process steps of preparing a first suspension containing powder ceramic, solvent and dispersant mixture by slip casting method, molding the first suspension mixture and allowing it to dry from outside to inside, pouring excessive (residual) slip (first suspension) out of the mold when it reaches to desired thickness, removing the material shaped to form compact part (6) of the bone cortical layer from the mold, preparation of the second suspension mixture comprising powder ceramic, solvent, dispersant and binder for the formation of the trabecular part (5) by freeze drying, cooling the second suspension until the liquid (1) is frozen so as to form trabecular part (5), obtaining the solid (2) by removing the free water in the substance to be dried in the first drying phase, removing the relative water to obtain vapor (3) in the second drying phase.