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Targeted Self-Assembly of Functionalized Carbon Nanotubes on Tumors
Targeted Self-Assembly of Functionalized Carbon Nanotubes on Tumors
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机译:肿瘤上的官能化碳纳米管的靶向自组装
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摘要
Provided herein are single wall nanotube constructs to which are convalently linked a plurality of a bifunctional chelator, a therapeutic or a diagnostic radionuclide chelated to each bifunctional chelator and a plurality of morpholino oligonucleotides conjugated to the single wall nanotube. Also provided are single wall nanotube complexes which have the morpholino oligonucleotides on the single wall nanotube constructs hybridized to other morpholino oligonucleotides. The other morpholino oligonucleotides are each conjugated to a therapeutic antibody.
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