A novel anti Lam and anti-pim6 / Lam monoclonal antibody for diagnosis and treatment of Mycobacterium tubercularis infection

摘要

Mycobacterium tuberculosis infection Provide compositions, kits, vectors, and methods containing epitope specific antibodies found in lipoarabinomannan (LAM) lipomannan (LM) and phosphatidylino-inositol mannoside 6 (pim6).A human monoclonal anti lipoarabinomannan (anti Lam) antibody having a specific sequence, specifically associated with the lam epitope comprising an AR4 structure, an Ar6 structure, or a combination thereof, or its antigen binding portion.Diagram