ACTIVE GENE MODIFIED PORCINE SKIN FOR COVERING AND REPAIRING HUMAN SKIN WOUNDS AND USE THEREOF

摘要

Provided are an active gene modified porcine skin for covering and repairing human skin wounds, and a use thereof. The porcine skin has porcine immune antigens GGTA, B4GAL and CAMH removed therefrom, and contains a combination of human CD55, 59, 46, 47, 39, 141, HLEA and TFPI proteins. The resulting ex-vivo porcine skin can be used for covering and closing skin wounds and can recover effective blood circulation and complete skin functions for the wounds. Moreover, the porcine skin can save the lives of patients, promote wound repair, and reduce the formation of scars; and the difficulty in the prior art whereby porcine skin transplanted on skin wounds cannot survive can be solved.