NANOSTRUCTURED MATERIAL WITH INTERFEROMETRIC PROPERTIES FOR THE VISUAL DETECTION OF BIORECOGNITION ASSAYS WITHOUT LABELLING

摘要

The present invention refers to a nanomaterial that allows chemical and biochemical analysis to be carried out and the result thereof to be determined by direct visual detection, without using labels (label-free) and without requiring any type of instruments. The material is formed by a layer of bioreceptors that selectively interact with analytes and which is disposed on an interferometric layer deposited on a substrate. Incubation of samples on the material produces changes in its interferometric response, which translate into colour changes that are directly observable visually under natural or artificial light, the magnitude thereof depending on the concentration of the analyte present in the sample.