12-c-3- Novel dihydroindeno12-cpyrazole-3-carboxamide derivatives and pharmaceutical composition for preventing or treating neurodevelopmental disorders or neurodegenerative diseases comprising the same

摘要

The present invention relates to a novel dihydroindeno[1,2-c]pyrazole-3-carboxamide derivative and a pharmaceutical composition for preventing or treating neurodevelopmental disorders or neurodegenerative diseases comprising the same as an active ingredient, It is possible to provide a compound useful as a composition for preventing or treating neurodevelopmental disorders or neurodegenerative diseases due to its excellent GSK3β inhibitory activity and excellent NFκB activity inhibition and Wnt/β-catenin signaling system activation efficacy in MeCP2-depleted cells.