-- VIOLACEIN-ZINC OXIDE-POLYMER COMPOSITE NANOFIBER WITH ANTIBIOTIC ABILITY TOWARD METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AND THEIR FABRICATION METHOD

摘要

In the embodiments of the present invention, one-dimensional nanofibers containing violacein having antibacterial ability against MRSA (Methicillin-Resistant Staphylococcus Aureus), which are caused by resistance to antibiotics, have a three-dimensional structure It relates to a violacein-zinc oxide-polymer composite nanofiber antibacterial membrane and a method for manufacturing the same, which can be used as an antibacterial membrane for preventing and treating MRSA infection. Specifically, by dissolving a high amount of violacein in a solution in which a polymer is dissolved to prepare a solution in which violacein is uniformly mixed, and by synthesizing a nanofiber membrane through an electrospinning process, viola inside and outside the nanofiber It is differentiated from the conventional method of applying materials to the surface of fibers as it is characterized in that the sein is uniformly contained without agglomeration. Since the embodiments of the present invention use the electrospinning technique, it is possible to mass-produce nanofiber membranes that can control the distribution of pores by simply controlling the thickness and spacing of the nanofibers, so that they can be used inexpensively and conveniently, as well as moisture and moisture. It can be used for a long time by attaching the antibacterial membrane manufactured with excellent wettability to the skin and infected areas. The violacein-zinc oxide-polymer composite nanofiber antibacterial of the present invention improves the limitations of existing preventive measures and treatments for MRSA, and conveniently for prevention and treatment of MRSA in individuals or treatment institutions such as hospitals A membrane may be utilized.