VIOLACEIN―POLYMER COMPOSITE NANOFIBER WITH ANTIBIOTIC ABILITY TOWARD METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AND THEIR FABRICATION METHOD

摘要

Examples of the present invention are nanofibers of a one-dimensional shape containing violacein having antibacterial ability against MRSA (Methicillin-Resistant Staphylococcus Aureus, methicillin-resistant Staphylococcus aureus) bacteria caused by resistance to antibiotics. It relates to a violacein-polymer composite nanofiber antibacterial membrane formed by entangled with and a manufacturing method thereof, and can be used as an antibacterial membrane for preventing and treating MRSA infection. Specifically, by dissolving a high amount of violacein in a solution in which a polymer is dissolved, a solution in which violacein is uniformly mixed is prepared, and the nanofiber membrane is synthesized through an electrospinning process. It is distinguished from the method of applying the material to the conventional fiber surface by the feature that the sein is uniformly included without agglomeration. Since the embodiments of the present invention use the electrospinning technique, a nanofiber membrane capable of controlling the distribution of pores by simply adjusting the thickness and spacing of the nanofibers can be mass-produced and utilized inexpensively and conveniently, as well as moisture and It can be used for a long time by attaching the manufactured antibacterial membrane to the skin and infected areas with excellent wettability. The violacein-polymer composite nanofiber antimicrobial membrane of the present invention is used to improve the limitations of the existing preventive measures and treatments for MRSA, and for the prevention and treatment of MRSA easily in treatment institutions such as individuals or hospitals. Can be.