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Ultra-low dose THC as a potential therapeutic and prophylactic agent for Alzheimer's disease
Ultra-low dose THC as a potential therapeutic and prophylactic agent for Alzheimer's disease
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机译:超低剂量THC作为阿尔茨海默病的潜在治疗和预防剂
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摘要
Alzheimer's disease is treated using THC (alone, or in combination with melatonin) administered in an ultra-low dose amount sufficient to (i) reduce Aß expression; (ii) reduce Aß aggregation: (iii) maintain APP expression; (iv) enhance mitochondrial functioning; (v) decrease phosphorylation of GSK3ß protein; (vi) decrease the expression of GSK3ß protein; (vii) decrease phosphorylation of Tau protein; and/or (viii) maintain Tau protein expression, in said patient without severe psychological impairments and side effects associated with higher doses of THC.
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