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QUINAZOLINE-PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CANCER-RELATED DISORDERS

机译:喹唑啉 - 吡唑衍生物治疗癌症相关疾病

摘要

A compound that is an inhibitor of at least one of the A2A and A2B adenosine receptors, and compositions containing the compound and methods for synthesizing the compound, are described herein. The use of such compound and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by the adenosine A2A receptor and/or the adenosine A2B receptor.
机译:本文描述了一种化合物,其是A 2a-sup>和 2b 腺苷受体中的至少一种的抑制剂,以及含有化合物的化合物的组合物和用于合成化合物的方法。使用这些化合物和组合物用于治疗不同疾病,疾病和病症的各种疾病,包括癌症和免疫相关疾病,其至少部分地由腺苷A 2a 受体和/或腺苷A 2b 受体。

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