IMMUNOGENIC CONJUGATE INTENDED FOR INDUCING AN IMMUNE RESPONSE AGAINST INTERLEUKIN 6

摘要

The invention relates to an immunogenic conjugate, comprising:-Carrier protein and-At least one polypeptide having no more than 100 amino acids, including 5-50 amino acid sequences of interleukin-6 (IL-6) or IL-6 receptor (IL-6R), or a variant having at least 75% homology with 5-50 amino acid sequences of IL-6 or IL-6R,The polypeptide covalently binds to the carrier protein, which is a nontoxic mutant diphtheria toxin.