A composition with antiviral activity which comprises water-soluble extracts of Macrocystis pyrifera substantially alginate-free and a carrier or vehicle, and method for obtaining same. Wherein this composition serves to prepare a topical antiviral medicinal product for preventing or treating skin or oral lesions caused by herpes viruses of the subfamily Alphahehrpesvirinae, such as herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2) and varicella zoster virus (VZV), resistant or non-resistant to acyclovir (ACV).
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