COMPOUNDS FOR THE TREATMENT OF MYELOFIBROSIS

摘要

The present invention provides methods of treating myelofibrosis in a patient by administering to the patient a therapeutically effective amount of a 08Κ-3β inhibitor such as 3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-[l,3]dioxolo[4,5-f]indol-7-yl)pynOle-2,5-dione, or a pharmaceutically acceptable salt thereof, optionally in combination with a therapeutically effective amount of a JAK inhibitor such as ruxolitinib, or a pharmaceutically acceptable salt thereof.