PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING FIBROSIS COMPRISING PHEOPHORBIDE COMPOUNDS AS AN EFFECTIVE INGREDIENT

摘要

The present invention relates to a pharmaceutical composition for preventing or treating fibrosis comprising a pheophorbide-based compound as an active ingredient, and inhibits the activation and expression of collagen and fibronectin by inhibiting the signal transduction of TGF-β, which is the cause of fibrosis By doing so, it is possible to effectively inhibit tissue fibrosis, and since it has significantly superior anti-fibrotic activity compared to nintedanib or pirfenidone, which are currently commercially available pulmonary fibrosis therapeutics, it will be widely used in the prevention or treatment of fibrosis.