Formulations and methods of treatment for a patient infected with Sudan virus are provided. The formulation comprises a therapeutically effective combination of: (i). a first monoclonal antibody comprising a heavy chain variable region comprising an amino acid sequence deduced from the nucleic acid molecule as set forth in SEQ. ID NO: 5, and a light chain variable region comprising an amino acid sequence deduced from the nucleic acid molecule as set forth in SEQ ID NO: 6, therapeutically effective mutations, and humanized variants thereof, and humanized variants thereof; (ii). a second monoclonal antibody comprising a heavy chain variable region comprising an amino acid sequence deduced from the nucleic acid molecule as set forth in SEQ. ID NO: 13 and a light chain variable region comprising an amino acid sequence deduced from the nucleic acid molecule as set forth in SEQ ID NO: 14, therapeutically effective mutations, and humanized variants thereof.
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机译：提供了用苏丹病毒感染的患者的制剂和治疗方法。该制剂包含以下治疗有效的组合：（i）。包含重链可变区的第一单克隆抗体，其包含从SEQ中所述从核酸分子中推导的氨基酸序列。 ID NO：5和轻链可变区，其包含如SEQ ID NO：6，治疗有效突变和其人源化变体中所示的核酸分子所示的氨基酸序列，及其源化变体; （ii）。包含重链可变区的第二单克隆抗体，其包含从SEQ中所述从核酸分子中推导的氨基酸序列。 ID NO：13和轻链可变区，其包含由SEQ ID NO：14，治疗有效突变和人源化变体中列出的核酸分子中推导的氨基酸序列。
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