embedded image "/> Compositions and methods for treating cancer with a combination of programmed death receptor (PD-1) antibodies and a CXCR2 antagonist
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Compositions and methods for treating cancer with a combination of programmed death receptor (PD-1) antibodies and a CXCR2 antagonist

机译:用程序死亡受体(PD-1)抗体和CXCR2拮抗剂的组合治疗癌症的组合物和方法

摘要

The present invention relates to methods of treating a cell proliferation disorder (e.g., cancer) comprising administering: (a) a compound having the Formula (I), wherein R1 or R2 are as herein defined, or a pharmaceutically acceptable salt thereof; and (b) an anti-human PD-1 antibody or antigen binding fragment thereof to a human patient in need thereof. Also disclosed are therapeutic combinations and kits containing such agents for the treatment of cancers.; embedded image
机译:本发明涉及治疗细胞增殖障碍(例如,癌症)的方法,包括给予:(a)具有式(I)的化合物,其中R 1 或R 2 如本文定义,或其药学上可接受的盐; (b)对有此需要的人类患者的抗人PD-1抗体或其抗原结合片段。还公开了含有用于治疗癌症的药剂的治疗组合和试剂盒。 <化学ID =“Chem-US-00001”> “嵌入图像”文件=“US11052065-20210706-C00001.gif”他=“36.32mm”imgContent

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