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MULTIPLE ANTIGEN BINDING MOLECULAR FUSION, PHARMACEUTICAL COMPOSITION, METHOD FOR IDENTIFYING LINEAR EPITOPE, AND METHOD FOR PREPARING MULTIPLE ANTIGEN BINDING MOLECULAR FUSION
MULTIPLE ANTIGEN BINDING MOLECULAR FUSION, PHARMACEUTICAL COMPOSITION, METHOD FOR IDENTIFYING LINEAR EPITOPE, AND METHOD FOR PREPARING MULTIPLE ANTIGEN BINDING MOLECULAR FUSION
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机译:多种抗原结合分子融合,药物组合物,鉴定线性表位的方法,以及制备多种抗原结合分子融合的方法
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摘要
A multiple antigen-binding molecule fusion molecule containing a multiple antigen-binding molecule (±) having an immune cell antigen-binding region and a cancer antigen-binding region, a cancer tissue-specific protease-cleavable linker (²), and a masking molecule (³) containing a polypeptide having the amino acid sequence QDGNE, in which the multiple antigen-binding molecule (±) and the masking molecule (³) are linked via the cancer tissue-specific protease-cleavable linker (²).
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