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Compositions and methods for regulating activity of inhibitor of DNA binding-2 (ID2) protein and for treating ID protein-related diseases
Compositions and methods for regulating activity of inhibitor of DNA binding-2 (ID2) protein and for treating ID protein-related diseases
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机译:用于调节DNA结合-2(ID2)蛋白抑制剂活性和治疗ID蛋白质相关疾病的组合物和方法
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摘要
The present disclosure provides, in one embodiment, a method of treating or preventing an ID2 protein-related disease in a patient at risk of developing or having such a disease by administering to the patient a composition in an amount and for a time sufficient to increase degradation of HIFα in a cell affected by the ID2 protein-related disease in the patent and/or to decrease half-life of HIFα in the cell affected by the ID2 protein-related disease in the patient, as compared to an untreated cell affected by the ID2 protein-related disease.
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