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COMPOSITIONS AND METHODS FOR REGULATING ACTIVITY OF INHIBITOR OF DNA BINDING-2 (ID2) PROTEIN
COMPOSITIONS AND METHODS FOR REGULATING ACTIVITY OF INHIBITOR OF DNA BINDING-2 (ID2) PROTEIN
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机译:调节DNA结合2(ID2)蛋白抑制剂的活性的组合物和方法
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摘要
The present disclosure provides, in one embodiment, a method of treating or preventing an ID2 protein-related disease in a patient at risk of developing or having such a disease by administering to the patient a composition in an amount and for a time sufficient to increase degradation of HIFα in a cell affected by the ID2 protein-related disease in the patent and/or to decrease half-life of HIFα in the cell affected by the ID2 protein-related disease in the patient, as compared to an untreated cell affected by the ID2 protein-related disease.
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