Method for producing three-dimensional gingival epithelium model induced in periodontal disease state

摘要

Problem to be solved: to provide a means to infect periodontopathic bacteria in a three-dimensional human gingival epithelial model.In the normal human three-dimensional gingival epithelium model, the periodontopathic bacteria and the pathogenic factors were added to the keratinocytes, and culture was carried out under the anaerobic condition. Three dimensional human gingival epithelium model is derived from periodontal tissue.No selection