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Method for producing 1,1'-binaphthyl derivative and 1,1'-binaphthyl derivative

机译:制备1,1'-二氯基衍生物和1,1'-二氯基衍生物的方法

摘要

In the production method of the present disclosure, a 1,1′-binaphthyl precursor derivative having an electron-donating group containing an oxygen atom directly bonded to the skeleton at the 2-position and the 2′-position of the 1,1′-binaphthyl skeleton, An organic acid is mixed with an iodinating agent or brominating agent. According to the production method of the present disclosure, a 1,1′-binaphthyl derivative having a substituent introduced at the 8-position and / or the 8′-position of the 1,1′-binaphthyl skeleton can be obtained. The 1,1′-binaphthyl derivative obtained by the production method of the present disclosure is at least one selected from the 4-position, 4′-position, 5-position, 5′-position, 6-position and 6′-position of the 1,1′-binaphthyl skeleton. It may be a compound in which a substituent is further introduced at one position.
机译:在本公开的制备方法中,具有含有含有氧原子的1,1'-二萘基前体衍生物,其在2位和1,1'的2'-位置直接粘合到骨架上的氧原子 - 苯并骨基骨架,将有机酸与碘化剂或溴化剂混合。根据本公开的制备方法,可以获得在8-位和/或1,1'-二苯甲基骨架的8位位置引入的1,1'-二萘基衍生物。通过本公开的制造方法获得的1,1'-二氯基衍生物是选自4位,4'位置,5位,5'位置,6位和6'-位置的至少一种1,1'-硼酸骨骨架。它可以是其中进一步引入一个位置的化合物。

著录项

  • 公开/公告号JP6893360B2

    专利类型

  • 公开/公告日2021-06-23

    原文格式PDF

  • 申请/专利权人 国立大学法人京都大学;

    申请/专利号JP20180501114

  • 发明设计人 嶋田 豊司;中西 和樹;

    申请日2017-02-03

  • 分类号C07C303/26;C07C309/66;C07C46/02;C07C309/65;C07C50/32;

  • 国家 JP

  • 入库时间 2022-08-24 19:34:32

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