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ANTI-CANCER PRODRUG FOR OVERCOMING MULTIDRUG RESISTANCE
ANTI-CANCER PRODRUG FOR OVERCOMING MULTIDRUG RESISTANCE
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机译:延长多药抗性抗癌前药
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摘要
The present invention relates to an anti-cancer prodrug comprising a compound represented by [Formula 1] as stated below: The anti-cancer prodrug, according to the present invention, has high selectivity for cancer cells overexpressing COX-2, and selectively reacts to H2O2 and effectively releases two drugs, thereby overcoming multidrug resistance and improving anti-cancer effects.
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机译:抗癌前药技术领域本发明涉及抗癌前药,其包含如下所述的[式1]代表的化合物:根据本发明的抗癌前药具有过表达COX-2的癌细胞具有高选择性,并选择性地反应H 2 sub> O 2 sub>并有效地释放两种药物,从而克服多药抗性和改善抗癌作用。
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