Method for searching marker gene of chondrocyte sheet, marker gene searching device of chondrocyte sheet, evaluation method of chondrocyte sheet, evaluation device of chondrocyte sheet, cartilage cell sheet, method for producing chondrocyte sheet and cartilage regeneration method using cartilage cell sheet

摘要

Problem to be solved: to provide a marker gene search method for searching marker marker related to the effectiveness after cartilage transplantation of cartilage cell sheet used for cartilage regeneration from the cartilage cell sheet before transplantation.SolutionThe present invention relates toA measurement procedure for measuring the expression of genes in the cartilage cell sheet before transplantationGene expression and secretory protein of chondrocyte sheet after transplantation were evaluated using transplantation model.From the measurement result obtained in the measurement processAnalysis and analysis of gene expression profiles of chondrocyte sheets after transplantationBased on the gene expression profile analyzed in the analysis processA search procedure for searching genes that have positive correlation to posttransplant availability and / or negative correlation genesIs a marker gene search method of the chondrocyte sheet with the.Diagram