Active source pixel integrated devices for rapid analysis of biological and chemical samples

摘要

The present invention relates to an active source pixel integrated device capable of performing biomolecular detection and / or analysis such as single molecule nucleic acid sequencing.SolutionAn active pixel of the integrated device is a sample well and can be analyzed to sample a sample well and diffuse into a sample well and an excitation source for providing excitation energy to the sample well Includes sensors to detect emissions from samples.The sensor can be comprised of two or more segments that produce a set of signals, the set of signals is analyzed to identify between tags, and analyzed to identify the tag, attached to the sample, or associated with the sample.Tag differentiation can be a base and / or temporal basis of the spectrum.Identification of tags can be used to detect, analyze, and / or sequencing biomolecules.Selection diagram