METHOD FOR USING SMALL MOLECULE COMPOUNDS TO INDUCE HUMAN TUMOR CELLS TO BE DIRECTLY REPROGRAMMED INTO NON-ONCOGENIC CELLS

摘要

The disclosure includes a method of inducing direct reprogramming (transdifferentiation) into non-oncogenic cells accompanied by tumor cell apoptosis in human tumor cells using a small molecule composition, based on the mechanism of chemical-induction of direct cellular reprogramming. The disclosure also includes a small molecule composition used for the method, and culture media and agents prepared from the composition.