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AMP-ACTIVATED PROTEIN KINASE ACTIVATING COMPOUNDS AND USES THEREOF

机译:AMP-活化的蛋白激酶激活化合物及其用途

摘要

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they relate to the treatment and/or prevention of conditions associated with activation of AMP- activated protein kinase, wherein the compound is of Formula (I): as described herein, including pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising such compounds, as well as methods to use these compositions for treating indications including cancer, diabetes, ischemic injury, obesity, hyperlipidemia, and cardiac conditions.
机译:本发明涉及药物化合物,组合物和方法,特别是它们与治疗和/或预防与AMP-活化蛋白激酶的活化相关的病症,其中化合物是式(I):如本文所述,包括如本文所述,包括药学上可接受的盐及其包含这些化合物的药物组合物,以及使用这些组合物用于治疗包含癌症,糖尿病,缺血性损伤,肥胖症,高脂血症和心脏病的方法的方法。

著录项

  • 公开/公告号EP3833359A2

    专利类型

  • 公开/公告日2021-06-16

    原文格式PDF

  • 申请/专利权人 SKYLARK BIOSCIENCE LLC;

    申请/专利号EP20190857609

  • 发明设计人 SAUNDERS OLIVER;

    申请日2019-08-02

  • 分类号A61K31/7072;A61P35/02;

  • 国家 EP

  • 入库时间 2022-08-24 19:22:25

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