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Nanostructures containing cobalt porphyrin phospholipid conjugates and polyhistidine Tags

机译:含有钴卟啉磷脂偶联物和多亚氨酸标签的纳米结构

摘要

The present disclosure provides nanostructures (eg, monolayer or bilayer nanostructures) comprising porphyrin (with cobalt chelated therein), wherein the cobalt metal in the porphyrin macrocycle is Nanostructures present in a monolayer or bilayer are provided. The nanostructure may have a presentation molecule with a histidine tag attached, at least a portion of the His tag is in the monolayer or bilayer and is coordinated to a cobalt metal core, Molecules are exposed outside the nanostructure. The nanostructure may further include cargo. The nanostructure can be used to deliver the cargo to an individual. [Selection] Figure 1
机译:本公开提供了纳米结构(例如,单层或双层纳米结构),其包含卟啉(其中含有钴螯合物),其中卟啉大环中的钴金属是提供单层或双层中存在的纳米结构。纳米结构可以具有附着具有组氨酸标签的呈现分子,其标签的至少一部分位于单层或双层中,并与钴金属核心配位,分子暴露在纳米结构外部。纳米结构还可包括货物。纳米结构可用于将货物输送到个体。 [选择]图1

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