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Skin derived novel lactic acid bacteria having effects of enhancing skin barrier and anti-wrinkle and use thereof
Skin derived novel lactic acid bacteria having effects of enhancing skin barrier and anti-wrinkle and use thereof
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机译:皮肤衍生的新型乳酸菌具有增强皮肤屏障和抗皱和用途的影响
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摘要
The present invention relates to a novel lactic acid bacterium derived from skin having skin barrier strengthening and anti-wrinkle activity and uses thereof, and specifically, the present invention relates to a novel lactic acid bacterium isolated and identified from human skin, Lactobacillus plantarum seva-202 (Accession No. : KCTC14087BP) strain, Lactobacillus Fermentum sebacillus-101 (Accession No.: KCTC14086BP) strain or Lactobacillus paraplatanum sebba-401 (Accession No.: KCTC14088BP) strain and the new strain, its culture, its lysate or its extract It relates to a cosmetic composition for enhancing skin barrier function, a cosmetic composition for improving skin wrinkle, a food composition for enhancing skin barrier function, and a food composition for improving skin wrinkle, comprising as an active ingredient. The new skin-derived strain and the culture solution of the new strain according to the present invention have excellent ability to form a cornified envelope (CE) in skin cells and have inhibitory activity of elastase and hyaluronidase. It is excellent and can be usefully used in the production of functional cosmetics and functional foods having skin barrier function strengthening and anti-wrinkle activity.
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机译:本发明涉及一种新的乳酸细菌,所述乳酸细菌衍生自皮肤具有皮肤屏障强化和抗皱活性和其用途,具体地,本发明涉及分离的新型乳酸菌和从人体皮肤,Lactobacillus Plantarum Seva--的新乳酸菌。 202(登录号:KCTC14087BP)菌株,乳酸杆菌菌株-101(登录NO.:KCTC14086BP)菌株或乳杆菌钾钾肽SEBBA-401(登录号:KCTC14088BP)菌株和新菌株,其培养物,其裂解物或其萃取物它涉及一种用于增强皮肤屏障功能的化妆品组合物,一种用于改善皮肤皱纹的化妆品组合物,用于增强皮肤屏障功能的食物组合物,以及用于改善皮肤皱纹的食物组合物,包括作为活性成分。根据本发明的新的皮肤衍生的菌株和新菌株的培养溶液具有优异的形成皮肤细胞中的葡萄壳(CE)并具有弹性蛋白酶和透明质酸酶的抑制活性。它是优异的,可以有效地用于生产功能性化妆品和功能性食品,具有皮肤屏障功能强化和抗皱活动。
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