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TREATING HERPESVIRUS-MEDIATED INTESTINAL DYSFUNCTION FOR PREVENTION OF AGE-RELATED NEURODEGENERATION
TREATING HERPESVIRUS-MEDIATED INTESTINAL DYSFUNCTION FOR PREVENTION OF AGE-RELATED NEURODEGENERATION
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机译:治疗Herpesvirus介导的肠功能障碍以预防年龄相关的神经变性
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摘要
Human herpesviruses can infect barrier and immune cells of the intestines to cause microbiome dysbiosis and inflammation. Microbiome dysbiosis can affect the brain function, and inflammation can compromise the intestinal barrier and lead to microbial translocation. Embodiments may restrict herpesvirus activity and injury by 1) the oral administration of exosomes containing factors to inhibit viral activity and restore homeostasis, and 2) the oral administration of recombinant bacteria that produce exosomes containing factors to inhibit viral activity and restore homeostasis. Embodiments also measure HHV activity in stool by ELISA immunoassay of HHV proteins.
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