The present invention relates to a cell freeze-drying system, the cell freeze-drying system including a heated nitrogen gas supply mechanism, a freeze-drying operation box, and an exhaust mechanism, wherein the heated nitrogen gas supply mechanism and the freeze-drying operation are performed. The box and the exhaust mechanism are sequentially connected via a first connection pipe, and the heated nitrogen gas supply mechanism supplies heated nitrogen to the freeze-drying operation box, and the freeze-drying operation box After putting the cell sample frozen in liquid nitrogen, the temperature is raised according to a preset mode, and the gaseous nitrogen after heating is introduced continuously to sublimate the solid water of the cell sample to form gaseous water. The freeze-drying operation box is pre-adjusted to a temperature suitable for containing a cell sample frozen with liquid nitrogen, and the exhaust mechanism raises the solid water of the cell sample. Or to exhaust the gaseous nitrogen containing gas water formed by. The invention further relates to a method for freeze-drying cells. INDUSTRIAL APPLICABILITY The present invention can effectively solve the problem of damage and contamination due to freeze-drying of cells, and can achieve excellent safety, high efficiency and low cost of cell freeze-drying. [Selection diagram] Fig. 1
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