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Nucleic acid encoding anti-CD163 antibody or antigen binding fragment thereof, Adenovirus vector comprising the same, and use thereof in the prevention or treatment of African swine fever
Nucleic acid encoding anti-CD163 antibody or antigen binding fragment thereof, Adenovirus vector comprising the same, and use thereof in the prevention or treatment of African swine fever
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机译:编码抗CD163抗体或其抗原结合片段的核酸,包含相同的腺病毒载体,并在预防或治疗非洲猪瘟
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摘要
The present invention relates to a nucleic acid molecule encoding an anti-CD163 antibody or an antigen-binding fragment thereof, an adenovirus vector comprising the same, and a use of the anti-CD163 antibody or antigen-binding fragment thereof for the prevention or treatment of African swine fever. The adenovirus vector comprising the anti-CD163 antibody or antigen-binding fragment of the present invention and the nucleotide encoding the same exhibits the ability to inhibit the infection of the African swine fever virus in porcine alveolar macrophages, and thus for the prevention or treatment of African swine fever It can be usefully used as a formulation.
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