首页> 外国专利> Nucleic acid encoding anti-CD163 antibody or antigen binding fragment thereof, Adenovirus vector comprising the same, and use thereof in the prevention or treatment of African swine fever

Nucleic acid encoding anti-CD163 antibody or antigen binding fragment thereof, Adenovirus vector comprising the same, and use thereof in the prevention or treatment of African swine fever

机译:编码抗CD163抗体或其抗原结合片段的核酸,包含相同的腺病毒载体,并在预防或治疗非洲猪瘟

摘要

The present invention relates to a nucleic acid molecule encoding an anti-CD163 antibody or an antigen-binding fragment thereof, an adenovirus vector comprising the same, and a use of the anti-CD163 antibody or antigen-binding fragment thereof for the prevention or treatment of African swine fever. The adenovirus vector comprising the anti-CD163 antibody or antigen-binding fragment of the present invention and the nucleotide encoding the same exhibits the ability to inhibit the infection of the African swine fever virus in porcine alveolar macrophages, and thus for the prevention or treatment of African swine fever It can be usefully used as a formulation.
机译:本发明涉及编码抗CD163抗体或其抗原结合片段的核酸分子,其包含相同的腺病毒载体,以及用于预防或治疗的抗CD163抗体或抗原结合片段的用途非洲猪瘟。包含本发明的抗CD163抗体或抗原结合片段的腺病毒载体和编码的核苷酸相同表现出抑制猪肺泡巨噬细胞中非洲猪瘟病毒感染的能力,从而用于预防或治疗非洲猪瘟它可以用作配方。

著录项

  • 公开/公告号KR102254246B1

    专利类型

  • 公开/公告日2021-05-20

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020200035235

  • 发明设计人 송주연;

    申请日2020-03-23

  • 分类号C07K16/28;A61K39;A61P31/20;C07K19;C12N15/86;

  • 国家 KR

  • 入库时间 2022-08-24 18:58:22

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