Vaccine composition of the inactivated-pathogenic Escherichia coli whole cells using extracts of silk worm induced an immune response

摘要

The present invention relates to a pathogenic Escherichia coli inactivated dead cell vaccine composition capable of preventing Escherichia coli in piglets, a feed additive comprising the same, and a method for preventing Escherichia coli in piglets using the same. In addition, the present invention relates to a composition for producing a vaccine for preventing weaning piglet coliosis, comprising a silkworm extract containing an antibacterial peptide. Since the inactivated dead cell vaccine treated with silkworm extract of the present invention can exhibit an effective protective effect against F4+ and F18+ ETEC, which is a problem in weaned piglets, it effectively prevents diarrhea and edema disease occurring in weaned piglets, and coliosis of weaned piglets. Can effectively mute.