Artificial RNA restriction enzyme

摘要

The present invention addresses the problem of providing an artificial RNA restriction enzyme with which it is possible to disable an RNA virus such as an influenza virus by cleavage. The invention is an artificial RNA restriction enzyme formed by linking an RNA-binding protein that binds with RNA and an enzyme that cleaves a predetermined site of the RNA, via a peptide linker. The invention is also characterized in that the length of the peptide linker is five amino acids when the enzyme linked via the peptide linker is an SNase and the length of the peptide linker is five amino acids or ten amino acids when the enzyme linked via the peptide linker is a PIN.