Immunodeficient Animal Model with Mutation in IL2Rg Gene and Method for Producing the same

摘要

The present invention relates to an IL2Rg gene mutant immunodeficiency animal model and a method for manufacturing the same, and can induce immune failure in animals by deletion of T, B and NK cells in spleen cells, through which efficient xenograft of human cancer cell lines As this becomes possible, it is possible to manufacture an animal model that can be effectively used for research on immune-related diseases, for example, diseases such as cancer.