METHOD OF DETERMINING THE PRESENCE OF A HYPER-VIRULENT CLOSTRIDIOIDES DIFFICILE STRAIN OF THE B1/NAP1/027 GROUP IN A SAMPLE

摘要

The present invention relates to primer pair and an oligonucleotide probe for hybridizing to at least a portion of a chloramphenicol acetyltransferase gene coded in a transposon of family CTn-027 of a hyper-virulent Clostridioides difficile strain of the B1/NAP1/027 group, an oligonucleotide set for use in a nucleic acid amplification process or a nucleic acid detection process for determining the presence of a hyper-virulent Clostridioides difficile strain of the B1/NAP1/027 group in a sample, a kit for detecting the presence of a hyper-virulent strain of Clostridioides difficile of the B1/NAP1/027 group in a sample, and a method of determining the presence or absence of a hyper-virulent Clostridioides difficile strain of the B1/NAP1/027 group in a sample.