COMPOSITION, COMPRISING TMEM176B OR AN EXPRESSION OR ACTIVITY REGULATOR THEREOF AS AN ACTIVE INGREDIENT, FOR PREVENTION OR TREATMENT OF DEGENERATIVE BRAIN DISEASE

摘要

The present invention relates to a composition, comprising TMEM176B as an active ingredient, for prevention or treatment of degenerative brain disease. A composition according to an embodiment promotes the phagocytic action of astrocytes on amyloid-beta, reduces amyloid plaques, and improves behavioral and cognitive functions in Alzheimer animal models, thus finding advantageous applications in preventing and/or treating various degenerative brain diseases.