Cell-free nucleic acids for the analysis of human microbiomes and their components

摘要

PROBLEM TO BE SOLVED: To provide a method, an apparatus, a composition and a kit for analysis of a microbiome or an individual component thereof in an individual. A method for determining the presence and prevalence of microbial sequences in a sample of cell-free nucleic acid from a non-microbial host, wherein (i) a sample of cell-free nucleic acid from an individual is prepared and (ii) the nucleic acid. High throughput sequencing is performed, (iii) bioinformatics analysis is performed, the host sequence is subtracted from the analysis, and (iv) the presence and prevalence of the microbial sequence is determined for microbiome evaluation of the non-microbial host. The method. [Selection diagram] None