APTAMER BIOSENSORS USEFUL FOR DETECTING HORMONES, HORMONE MIMICS, AND METABOLITES THEREOF

摘要

The present invention provides polynucleotides that bind to small molecules and methods of using the polynucleotides. In some embodiments, a method comprises detecting a small molecule with a polynucleotide. In other embodiments, a method comprises administering a polynucleotide to inhibit the action of a small molecule. In some embodiments, the small molecule is a hormone, a hormone mimic, phytoestrogen, opiate, opioid, endocrine disrupting compound, metabolite thereof, or variant thereof.