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METHODS AND SYSTEMS FOR ORAL MICROBIOME ANALYSIS

机译:口服微生物组分析的方法和系统

摘要

Described are platforms, systems, and methods for providing a recommendation for an individual regarding oral health based on an analysis of an oral biological sample from the individual. In one aspect, a method includes receiving a plurality of sequence reads of an oral biological sample collected from an individual, wherein each of the sequence reads corresponding to one or more nucleic acid molecules from at least one food source or at least one microorganism; determining an abundance by: taxonomically classifying the sequence reads to identify the at least one food source or the at least one microorganism; and quantifying the one or more nucleic acid molecules; processing the abundance through a machine learning algorithm to determine an indicator of an oral or gum disease in the individual; and providing, to a user interface, a recommendation for the individual regarding oral health.
机译:描述是基于来自个体的口腔生物学样本的分析提供关于口腔健康的个人的平台,系统和方法。在一个方面,一种方法包括接收从个体收集的口腔生物样品的多个序列读取,其中每个序列对应于来自至少一种食物来源或至少一种微生物的一个或多个核酸分子的读取;确定丰度:分类序列读取序列以鉴定至少一种食物来源或至少一种微生物;并定量一种或多种核酸分子;通过机器学习算法处理丰度,以确定个体口腔或牙龈疾病的指标;向用户界面提供关于口腔健康的个人的推荐。

著录项

  • 公开/公告号US2021142906A1

    专利类型

  • 公开/公告日2021-05-13

    原文格式PDF

  • 申请/专利权人 PREDENTOME INC.;

    申请/专利号US202117152657

  • 发明设计人 SOHEIL BIGDELI;

    申请日2021-01-19

  • 分类号G16H50/20;G16H50/30;G16H50/50;

  • 国家 US

  • 入库时间 2022-08-24 18:40:13

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