METHODS AND SYSTEMS FOR ORAL MICROBIOME ANALYSIS

摘要

Described are platforms, systems, and methods for providing a recommendation for an individual regarding oral health based on an analysis of an oral biological sample from the individual. In one aspect, a method includes receiving a plurality of sequence reads of an oral biological sample collected from an individual, wherein each of the sequence reads corresponding to one or more nucleic acid molecules from at least one food source or at least one microorganism; determining an abundance by: taxonomically classifying the sequence reads to identify the at least one food source or the at least one microorganism; and quantifying the one or more nucleic acid molecules; processing the abundance through a machine learning algorithm to determine an indicator of an oral or gum disease in the individual; and providing, to a user interface, a recommendation for the individual regarding oral health.