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Base composition for microneedle patch and microneedle patch containing this base composition
Base composition for microneedle patch and microneedle patch containing this base composition
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机译:微针贴剂的基础组合物和含有该基础组成的微针贴剂
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摘要
PROBLEM TO BE SOLVED: To not only smoothly release a microneedle patch in a manufacturing stage, but also to obtain desired flexibility, flatness, flexibility and skin adhesion in a use stage, and to obtain moisture resistance in a storage stage. Providing a base composition for a microneedle patch and a microneedle patch containing the base composition. SOLUTION: The first HPMC contains a first hydroxypropyl methylcellulose (HPMC), a second HPMC, and a polyvinylpyrrolidone / vinyl acetate copolymer (PVP / VA), and the viscosity of the first HPMC is larger than the viscosity of the second HPMC. A base composition in which the weight ratio of the first HPMC to the second HPMC is 1: 0.1 or more and 1: 1.2 or less, and the amount of PVP / VA is 0.25% by weight or more and 2% by weight or less. [Selection diagram] None
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