METHOD FOR PRODUCING URSODEOXYCHOLIC ACID USING DEEP EUTECTIC SOLVENT

摘要

The present invention pertains to: a composition for producing ursodeoxycholic acid (UDCA), the composition containing a deep eutectic solvent, a 7 alpha-hydroxy steroid dehydrogenase (7αHSDH), and a 7 beta-hydroxy steroid dehydrogenase (7βHSDH); a UDCA production kit including the composition; and a method for producing UDCA from chenodeoxycholic acid (CDCA) by using 7αHSDH and 7βHSDH in the presence of a reaction solvent including the deep eutectic solvent. A composition for producing UDCA according to the present invention can be used to efficiently produce UDCA from CDCA by using an enzymatic reaction in which the reverse reaction does not occur, and thus can be widely used in the production of various products using UDCA.