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HUMAN CELLULAR MODEL FOR INVESTIGATING CORTICO-STRIATAL-MIDBRAIN NEURAL PATHWAYS
HUMAN CELLULAR MODEL FOR INVESTIGATING CORTICO-STRIATAL-MIDBRAIN NEURAL PATHWAYS
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机译:用于研究皮质纹状体中脑神经途径的人蜂窝模型
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摘要
Human striatal and midbrain organoids or spheroids are generated in vitro, which may be generated at least in part from human pluripotent stem (hPS) cells. Such spheroids model the regions of the human brain and comprise specific sets of cells that are associated with the striatum, including mature medium spiny neurons, and midbrain of a human, and that can be subsequently assembled with the cortex to form cortico-striatal-midbrain circuits in vitro.
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