Insensitivity time correction method in quantitative positron emission tomography (PET) reconstruction for various subjects and radioactivity distributions

摘要

To perform the image reconstruction method 100, the non-temporary computer-readable medium stores instructions that can be read and executed by the workstation 18 including at least one electronic processor 20. The method is a step of determining the singles rate of the plurality of radiation detectors in the frame of the imaging data detected by the plurality of radiation detectors 17; the energy correction coefficient Nwgt for each radiation detector is acquired in the frame of the imaging data. Steps to determine based on the energy spectrum distribution of gamma rays incident on the radiation detector; the singles effective counting time correction coefficient for each radiation detector is determined for the singles factor and the energy for the radiation detector. Steps to determine from the correction coefficient; Steps to determine the system coincidence effective counting time correction coefficient from the system singles rate; For each LOR of a plurality of simultaneous counting lines (LORs) connecting a pair of radiation detectors, for the LOR The step of determining the effective counting time correction coefficient from the determined singles effective counting time correction coefficient and the determined system coincidence counting effective counting time correction coefficient of the pair of radiation detectors connected by the LOR; and the imaging data. Includes the step of reconstructing the frame of the above using the effective counting time correction coefficient for the determined LOR;