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Hyperstable Constrained Peptides and Their Design

机译:不稳定的受限肽及其设计

摘要

Hyperstable constrained peptides and methods and apparatus for designing such peptides are provided. A computing device can determine a peptide backbone using a computing device. The computing device can place zero or more disulfide bonds in the peptide backbone. The computing device can design one or more peptide sequences based on the peptide backbone. The computing device can validate at least one validated peptide sequence of the one or more peptide sequences. An output can be generated based on the at least one validated peptide sequence.
机译:提供了用于设计这些肽的不可推测的受约束的肽和方法和装置。计算设备可以使用计算设备确定肽骨干。计算装置可以在肽骨架中放置零硫键。计算装置可以基于肽骨架设计一种或多种肽序列。计算装置可以验证一种或多种肽序列的至少一种验证的肽序列。可以基于至少一种验证的肽序列生成输出。

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